Reset Osmostat in an Infant with Failure to Thrive

Reset Osmostat in an Infant with Failure to Thrive

We are reporting an infant who was presented to our institution exhibiting a failure to thrive and hyponatremia. An extensive renal evaluation revealed resistive hyponatremia with normal renal glomerular and tubular function. Patient remained hyponatremic even after fluid restriction, salt loading and Fludrocortisone (Florinef) administration. Water deprivation and water loading tests were sugg...

An unusual case of an infant with failure to thrive.

An infant with respiratory distress and failure to thrive.

A 4-month-old male was referred to the Dept of Paediatric Surgery at the authors9 institution, for the investigation of respiratory distress, failure to thrive and complete situs viscerum inversus since birth. A chest radiograph obtained a few hours after birth showed situs viscerum inversus, left apical atelectasis, hyperinflation and hyperlucency of the remaining left lung, and a mild shift o...

An infant with repeated respiratory infections and failure to thrive.

KIRTI GUPTA, *SURJIT SINGH, *DHRUBAJYOTI SHARMA, #MINI P SINGH AND *MEENU SINGH From the Departments of Histopathology, *Pediatrics, and #Virology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. Correspondence to: Dr Kirti Gupta, Associate Professor, Department of Histopathology, Postgraduate Institute of Medical Education and Research, (PGIMER), Chandigar...

Adipsic hypernatremia with a reset osmostat.

D the wide variation in the daily intake of sodium and water, plasma osmolality and sodium are maintained within normal range by vasopressin [arginine vasopressin (AVP) or antidiuretic hormone (ADH)] secretion and thirst. The osmotic threshold for AVP secretion is 283 mOsm/kg and for thirst sense is 293 mOsm/kg. Hence, by the time plasma osmolality reaches the osmotic threshold for thirst, AVP ...